THE 7TH SYMPOSIUM ON THE NEUROVIROLOGY AND NEUROIMMUNOLOGY OF SCHIZOPHRENIA AND BIPOLAR DISORDER – FOCUS ON GENOMICS, PROTEOMICS AND CLINICAL TRIALS WAS A HUGH SUCCESS. ABSTRACTS AND SLIDES FROM THE MEETING ARE NOW ON THIS SITE. CLICK HERE TO VIEW WE THANK EVERYONE FOR THEIR PARTICIPATION WE WILL NOT HAVE A GENERAL MEETING FOR 2002. WE …
IN VIVO BRAIN IMAGING AND DRUG DEVELOPMENT Clinton Kilts, Emory University School of Medicine, Atlanta, GA Major barriers exists to new drug development in psychiatry. Such barriers include an incomplete understanding of the pathophysiology of psychiatric disorders, of the adaptive brain response related to the therapeutic response to a course of treatment of the brain …
GENE EXPRESSION ANALYSIS OF THE POSTMORTEM BRAINS AND LYMPHOBLASTS IN BIPOLAR DISORDER Tadafumi Kato Laboratory for Molecular Dynamics of Mental Disorders, Brain Science Institute, RIKEN, Saitama, Japan We performed gene expression analysis in 60 postmortem prefrontal cortices of the Stanley Foundation Brain Collection. Down-regulation (HTR2C, CACNA1A, GRM1, GRIK1) or …
GENE EXPRESSION ANALYSIS OF THE POSTMORTEM BRAINS AND LYMPHOBLASTS IN
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MICROARRAY ANALYSIS OF THE STANLEY BRAIN COLLECTION Pamela Sklar, Whitehead Institute To identify genes involved in psychiatric disorders, we performed microarray expression profiling using Affymetrix gene-chips (~12,000 genes) on post-mortem prefrontal cortex (area 46) and cerebellum samples from 15 each of control, schizophrenia, bipolar disorder, and depression patients. We initially investigated all samples from prefrontal …
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Archives of General Psychiatry, 2003; in press Antibodies to Herpes Simplex Virus Type 1 Is Associated With Cognitive Deficits in Individuals With Schizophrenia Faith B. Dickerson, John J. Boronow, Cassie Stallings, Andrea E. Origoni, Inna Ruslanova, Robert H. Yolken BACKGROUND: Cognitive deficits are a characteristic feature of schizophrenia and contribute to the profound disabilities associated …
SINE-R.C2 (A HOMO SAPIENS SPECIFIC RETROPOSON) IS HOMOLOGOUS TO cDNA FROM POST-MORTEM BRAIN IN SCHIZOPHRENIA AND TO TWO LOCI IN THE Xq21.3/Yp BLOCK LINKED TO HANDEDNESS AND PSYCHOSIS Heui-Soo Kim*1, Rekha V. Wadekar1, Osamu Takenaka2, Catharine Winstanley3, Fusako Mitsunago2, Takashi Kageyama2, Byung-Hwa Hyun4, and Timothy J. Crow1. 1Department of Psychiatry, Warneford Hospital, University of Oxford, …
SINE-R.C2 (A Homo Sapiens Specific Retroposon) is
Homologous to cDNA from Post-Mortem Brain in Schizophrenia and to
Two Loci n the Xq21.3/Yp Block Linked to Handedness and Psychosis Read More »
DEFICIENT CALCIUM-DEPENDENT NITRIC OXIDE SYNTHASE ACTIVITY IN THE PREFRONTAL CORTEX OF SCHIZOPHRENIA AND DEPRESSION Guoqiang Xing, Mikulas Chavko, and Robert Post USUHS, Bethesda, MD Brain nitric oxide (NO), a molecule synthesized by NO synthase (NOS) has multiple functions in neural development, neuroprotection, brain plasticity, neurotoxicity, and behavior. The calcium-dependent constitutive NOS activity consists of neuronal …
ANGIOCENTRIC CD3+ T-CELL INFILTRATES IN HIV-1-ASSOCIATED CNS DISEASE IN CHILDREN C.D. Katsetos1, J.E. Fincke1, A. Legido2, H.W. Lischner2, J.-P Chadarevian3, E.M. Kaye2, C.D. Platsoucas1, and E.L.Oleszak4*. 1Department Microbiology & Immunology, Fels Institute of Cancer Research & Molecular Biology; 2Temple University School of Medicine, Department of Pediatrics; 3Department Anatomic Pathol. St. Christophers Hosp Children, Allegheny University; …
Angiocentric CD3+ T-Cell Infiltrates in HIV-1-Associated CNS Disease in Children Read More »
J. Neurovirol 2000 Dec;6(6):492-7 Serum Antibodies Reactive With Non-Human Primate Retroviruses Identified In Acute Onset Schizophrenia Lillehoj EP, Ford GM, Bachmann S, Schroder J, Torrey EF, Yolken RH Schizophrenia is a pervasive neuropsychiatric disease of uncertain etiology. Previous studies have postulated that retroviruses may contribute to the etiology of some cases of …
GENOME-WIDE EXPRESSION ANALYSIS REVEALS DYSREGULATION OF MYELINATION-RELATED GENES IN CHRONIC SCHIZOPHRENIA Kenneth L. Davis, Joseph Buxbaum, Monte Buchsbaum, Philip D. Harvey, Patrick R. Hof, Joseph I. Friedman, Daniel G. Stewart, Yaron Hakak, Allen A. Fienberg, Vahram Haroutunian The Mount Sinai School of Medicine, Department of Psychiatry, One Gustave L. Levy Place, New York, NY 10029 …
