Author name: Stanleylab

VIRUSES AND SCHIZOPHRENIA; A FOCUS ON HERPES SIMPLEX VIRUS

Herpes 11:2(Suppl):83A-88A, 2004 Robert Yolken ABSTRACT: Various factors have been implicated in the pathogenesis of schizophrenia. Evidence for an infectious cause includes the 508% increased risk among those born in the winter-spring months, when infectious diseases are more prevalent and at times when other infections (measles, varicella, poliomyelitis) show increased activity. Herpes simplex virus (HSV) …

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TOXOPLASMA ANTIBODY TITERS IN TREATMENT NAIVE FIRST EPISODES OF SCHIZOPHRENIA

To explore the contribution of infectious exposure to schizophrenia, we determined the levels of several antibodies to infectious agents in blood samples collected in a randomized double-blind 52 week clinical trial in China.  The sample included 160 first-episode schizophrenia patients and 60 normal controls balanced in distribution of age (28 ±7), gender (53% male vs. …

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CENTRAL NERVOUS SYSTEM AND SYSTEMIC QUINOLINIC ACID IN SCHIZOPHRENIA

CENTRAL NERVOUS SYSTEM AND SYSTEMIC QUINOLINIC ACID IN SCHIZOPHRENIA LD Bobo*, RH Yolken, EF Torrey, JD Paltan-Ortiz, MM Herman, NC Briggs, H Velasco, M Zito, MP Heyes Stanley Research Foundation, NAMI, Washington DC Immunologic marker elevations in schizophrenia have been reported. Quinolinic acid (QUIN), a potential neurotoxic product of immune-activated macrophages and microglia, has been …

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Publication

VIRUSES AND SCHIZOPHRENIA; A FOCUS ON HERPES SIMPLEX VIRUS Herpes 11:2(Suppl):83A-88A, 2004 Robert Yolken ABSTRACT: Various factors have been implicated in the pathogenesis of schizophrenia. Evidence for an infectious cause includes the 508% increased risk among those born in the winter-spring months, when infectious diseases are more prevalent and at times when other infections (measles, …

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Welcome

The overall goal of The Stanley Neurovirology Laboratory of the Johns Hopkins University School of Medicine is to develop a training and research program devoted to the elucidation of the role of infection and immunity in the etiology of schizophrenia and bipolar disorders. Consumers: See Department/Programs

Comparative Immunovirological Investigations of HHV-6, HHV-7, and HHV-8 in Multiple Schlerosis (MS), Other Neurological Disorders (OND), and Healthy Donors (HD)

COMPARATIVE IMMUNOVIROLOGICAL INVESTIGATIONS OF HHV-6, HHV-7, AND HHV-8 IN MULTIPLE SCLEROSIS (MS), AND OTHER NEUROLOGICAL DISORDERS (OND), AND HEALTHY DONORS (HD) *D.V. Ablashi1,2, J. Friedman3, G. Pearson2, J. Zabriskie3, and J.E. Whitman1 1Advanced Biotechnologies Inc., Columbia, MD; 2Georgetown Univ Sch of Med, Washington DC; 3Lab of Clin Microbiology/Immunology, Rockefeller Univ New York, NY Previous reports …

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ABSTRACT SUBMISSION

THE 7TH SYMPOSIUM ON THE NEUROVIROLOGY AND NEUROIMMUNOLOGY OF SCHIZOPHRENIA AND BIPOLAR DISORDER – FOCUS ON GENOMICS, PROTEOMICS AND CLINICAL TRIALS WAS A HUGH SUCCESS.   ABSTRACTS AND SLIDES FROM THE MEETING ARE NOW ON THIS SITE.  CLICK HERE TO VIEW  WE THANK EVERYONE FOR THEIR PARTICIPATION WE WILL NOT HAVE A GENERAL MEETING FOR 2002.  WE …

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Stanley Division of Developmental Neurovirology | Publications

COMPARING PHYLOGENETIC CODIVERGENCE BETWEEEN POLYOMAVIRUSES AND THEIR HOSTS J Virol. 2006 Jun;80(12):5663-9 Perez-Losada M, Christensen RG, McClellan DA, Adams BJ, Viscidi RP, Demma JC, Crandall KA Department of Integrative Biology, Brigham Young University, Provo, UT 84602-5181, USA. [email protected] ABSTRACT Seventy-two full genomes corresponding to nine mammalian (67 strains) and two avian (5 strains) polyomavirus species …

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Stanley Division of Developmental Neurovirology | Publications

IN VITRO INHIBITION OF TOXOPLASMA GONDII BY FOUR NEW DERIVATIVES OF ARTEMISININ Antimicrob Agents Chemother 50(12):4206-4208, 2006 Jones-Brando, L, D’Angelo J, Posner GH, Yolken R Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Baltimore, MD 2128-4988, USA, [email protected] ABSTRACT: Toxoplasmosis, caused by the protozoan Toxoplasma …

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IN VIVO BRAIN IMAGING AND DRUG DEVELOPMENT

IN VIVO BRAIN IMAGING AND DRUG DEVELOPMENT Clinton Kilts, Emory University School of Medicine, Atlanta, GA Major barriers exists to new drug development in psychiatry.  Such barriers include an incomplete understanding of the pathophysiology of psychiatric disorders, of the adaptive brain response related to the therapeutic response to a course of treatment of the brain …

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