Clin Infect Dis 2001 Mar 1

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Clin Infect Dis 2001 Mar 1;32(5):842-4

Antibodies To Toxoplasma Gondii In Individuals With First-Episode

Schizophrenia

Yolken RH, Bachmann S, Ruslanova I, Lillehoj E, Ford G, Torrey EF,

Schroeder J

We employed enzyme immunoassay (EIA) and Western blotting techniques to

measure the level of antibodies to Toxoplasma gondii proteins in serum samples

from 38 individuals undergoing their first episode of schizophrenia and from a

group of matched control subjects.  We found that the individuals with

first-episode schizophrenia had significantly increased levels of IgG, IgM, and

IgA class antibodies to Toxoplasma proteins, as compared with the control

subjects.