2nd Symposium on
The Neurovirology and Neuroimmunology of Schizophrenia and
title to view abstract
Thursday, November 14, 1996
8:00-9:00: Check in and Continental Breakfast
THE STANLEY NEUROVIROLOGY LABORATORY OF THE JOHNS
9:00: Robert H. Yolken:
Overview of the Stanley Laboratory Program-Do We Really Think
that Infections Can Cause Human Psychiatric Diseases.
9:20: Frances Yee:
and Virus-Related RNA Transcripts Are Differentially Expressed in
the Brains of Individuals with Schizophrenia.
9:40: Linda Bobo:
Correlation of Schizophrenia and Bipolar Disorder with Cytokine
and Cytokine Receptors in Ventricular Fluids and Postmortem Brain Tissue.
10:00: Nancy Johnston:
Measurement of RNA from 89 Postmortem Human Brains; A
Multivariate Statistical Analysis of Pre- and Post Mortem Effects
on the Yields of GAPdH As Measured by RT-PCR.
10:20: Indra De:
of Viral Particles in Glial Cells Inoculated with Brain Tissue
from Individuals with Schizophrenia and Bipolar Disease.
10:40: COFFEE BREAK
11:00: Yeping Sun:
Analysis of Gene Expression of Human Brain Tissue.
11:20: Raphael Viscidi:
Genomic Differential Display Enriched for Retroviral LTR
SESSION II: OTHER
NEUROLOGICAL AND INFECTIOUS DISEASES-WHAT CAN BE APPLIED TO THE
UNDERSTANDING OF SCHIZOPHRENIA AND BIPOLAR DISEASE
1:30: Sangram S. Sisodia, Johns Hopkins University,
Department of Pathology and Neurosciences, Baltimore, MD:
2:00: Christopher Ross, Johns Hopkins University,
Department of Neurobiology, Baltimore, MD: Genetics of Huntington’s Disease: Lessons for
2:30: Krister S. Kristensson, Karolinska Institutet,
Department of Neurosciences, Stockholm, Sweden: Trypanosoma Brucei Dysregulates the Mammalian
3:00: Lorraine Jones-Brando, Johns Hopkins University,
The Stanley Neurovirology Laboratory, Baltimore, MD:
3:35: Shizuku Sei, National Institutes of Health, NCI,
Bethesda, MD: Virological Aspects of
Neuropathogenesis of HIV-1 Disease.
3:55: Larisa Cervenakova, National Institutes of
Health, Laboratory of the Central Nervous System Studies,
Bethesda, MD: DNA Polymorphism and
Susceptibility to Environmentally Acquired Creutzfeldt-Jakob
4:15: Steven Jacobson, National Institutes of Health,
Association of HHV-6 and Multiple Sclerosis.
4:35: Dharam V. Ablashi, Georgetown University Medical
School, Washington DC: Higher
Frequency of Human Herpesvirus-6 (HHV-6) Antibody in Cerebral
Spinal Fluids and Sera from Multiple Sclerosis Patients.
SESSION III: POSTERS
7:00-8:00: Poster Viewing
(Wine and Cheese provided)
Arlene Collins, SUNY,
Department of Microbiology, Buffalo, NY: Susceptibility of Human Macrophages to
Paromita Deb, The
University of Western Ontario, Department of Zoology, London,
Ontario: Investigation of
Insertional Mutagenesis of “Retroid” Elements in the
Human Genome with Reference to Schizophrenia.
John H. Gilmore, University
of North Carolina School of Medicine, Department of Psychiatry,
Chapel Hill, NC: Neonatal Infection
Increases Neurotrophic Factor mRNA.
Frederick W. Hickling,
Psychotherapy Associates, Connoley House, Kingston, Jamaica:
Affective Disorder in Jamaica.
Nancy Johnston, Johns
Hopkins University, Stanley Neurovirology Laboratory, Baltimore,
From the Brains of Normal and Schizophrenic Individuals Show Than
an Unusually High Number of Novel Sequences are Present in the
Brain of the Schizophrenic Individual.
Timothy A. Klempan, The
University of Western Ontario, Department of Zoology, London,
Ontario: The Application and
Adaptation of Representational Difference Analysis in the
Evaluation of Retroviral Hypothesis for Schizophrenia.
Mark H. Rapaport,
University of California San Diego, Department of Psychiatry, La
Jolla, CA: A Pilot Study of Cytokine
and Soluble Interleukin-2 Receptor Levels in Symptomatic Bipolar
Effect of HTLV-1 Virus, IFN-y and Quin Precursors on Quin
Response in Cultured Human Monocytes and Macrophages.
Discussions and Answer
Friday, November 15, 1996
SESSION I: INFECTIONS AND
HUMAN PSYCHIATRIC DISEASES
9:00: Erling Norrby,
Karolinska Institute, Microbiology and Tumor Biology Center,
Stockholm, Sweden: Measles Virus
Invasion Through Limbic Structures in Mice with Disrupted Gene
for the Transporter Associated with Antigen Presentation.
10:00: Alan S. Brown, NYS Psychiatric Institute/Columbia
University, New York, NY: Psychosis
After Prenatal Exposure to Rubella.
10:20: Mady Hornig-Rohan, University of Pennsylvania,
University Science Center, Depression Research Unit,
Philadelphia, PA: Rates of Flu-Like
Illness in Patients with Affective Disorders.
11:00: W. John Martin,
Center for Complex Infectious Diseases, Rosemead, CA:
11:20: Susan Swedo, National Institutes of Mental
Health, Bethesda, MD: PANDAS: Is
There a New “Species” of Pediatric Neuropsychiatric
11:40: Brad D. Pearce, Emory University School of
Medicine, Department of Psychiatry, Atlanta, GA: The Immune Response in the Disruption of
Hippocampal GABA Circuits Following Neonatal Infection with
Lymphocytic Choriomeningitis Virus (LCMV).
SESSION II: IMMUNOLOGY AND
PATHOLOGY OF SCHIZOPHRENIA AND BIPOLAR DISEASE
1:30: Mark H. Rapaport, University of California San
Diego, Department of Psychiatry, LaJolla, CA: Evidence of Differences in Immune Function in
Older & Younger Schizophrenic Patients: Is This Age or A
Function of Severity of Illness.
1:50: Pinkhas Sirota, Abarbanel Mental Health Center,
Bat-Yam Felsenstein Medical Institute, Bat-Yam, Israel:
2:10: van Kammen, Daniel P., Department of Veterans
Affairs, Medical Center, Pittsburgh, PA: The Role of Immune Measures in Psychosis and
Stress Sensitivity in Schizophrenia.
2:30: Barbara B. Mittleman, NIMH, Unit on
Neuroimmunology, Behavioral Pediatrics Section, Child Psychiatry
Branch, Bethesda, MD: The Role of
Cytokines in Untreated and Treated Childhood Onset Schizophrenia.
3:10: Steve Zalcman, Concordia University, Department
of Psychiatry, Montreal, Canada:
3:30: Guoqiang Xing, National Institutes of Mental
Health, Bethesda, MD: PPARõ And Its
Potential Involvement in Schizophrenia.
3:50: Cassandra L. Smith, Boston University,
Departments of Biomedical Engineering, Biology and Pharmacology,
Boston, MA: Detection and
Quantitation of Genomic Differences in Microsatellites of
4:10: N.L. Anderson, Large Scale Biology Corporation,
Rockville, MD: Characterization of
Disease Processes and Pharmaceutical Mechanisms Through
Quantitative High-Throughput 2-D Electophoresis.
4:30: Jhy-Jhu Lin, Life Technologies, Inc (GIBCO/BRL),
Gaithersburg, MD: A New PCR-Based
DNA Fingerprinting Method: AFLP.
4:50: Janice R. Stevens, Oregon Health Sciences
University, Department of Psychiatry, Portland, OR:
Assist In the Search for Etiology?
SESSION III: EPIDEMIOLOGY
AND PATHOPHYSIOLOGY OF BORNA DISEASE
7:00: Kathryn Carbone, FDA, Laboratory of Pediatric
& Respiratory Viral Diseases, Bethesda, MD: Borna Disease Virus in Psychiatric Disease.
7:30: Juan C. de la Torre, The Scripps Research
Institute, La Jolla, CA: Borna
Disease Virus in Humans.
7:50: Royce W. Waltrip II, Maryland Psychiatric
Borna Disease Virus Serology in a First Episode Schizophrenia
8:10: Masahiko Kishi, Hokkaido University Institute of
Immunological Science, Section of Bacterial Infection, Sapporo,
Japan: Prevalence of Borna Disease
Virus RNA in Peripheral Blood Mononuclear Cells From Patients
with Affective Disorders.
8:30: D. Craig Hooper, Thomas Jefferson University,
Center for Neurovirology, Department of Microbiology and
Immunology, Philadelphia, PA: Is
Active Borna Disease Virus Infection Really a Contributor to
Human Psychiatric Disorders?
8:50: Joanne M. Pyper, Johns Hopkins University School
of Medicine, Division of Comparative Medicine, Baltimore, MD:
with Borna Disease Virus As Neonates.
Saturday, November 16, 1996
9:00: Stanley B. Prusiner, University of California San
The Molecular Biology and Genetics of Prion
Diseases: A Journey from Heresy to Orthodoxy.
10:00: E. Fuller Torrey, Guest Researcher, NIMH
Neurosciences Center, Washington DC:
Where Have We Been and Where are We Going: Risk Factors and
10:15: Robert H. Yolken, Director, The Stanley
Neurovirology Laboratory of the Johns Hopkins University,
Baltimore, MD: Closing Comments
Last revised on 05 June 2000.