3rd Symposium on the Neurovirology and Neuroimmunology of Schizophrenia and Bipolar Disorder

3rd Symposium on the Neurovirology and Neuroimmunology of Schizophrenia and Bipolar Disorder – October 23-25, 1997

Session I:  Presentations From the Stanley Laboratory, Johns Hopkins University School of Medicine

Abstract Presenter
Description of the Stanley Neuropathology Program E. Fuller Torrey
Individual Variations of Proten Species and Levels in Human Frontal Cortices: A Preliminary Study of Protein Variation Between Mentally Ill and Unaffected Individuals Nancy L. Johnston
Viral and Virus-Associated RNA Transcripts Are Differentially Expressed in the Brains of Individuals with Schizophrenia and Bipolar Disorder Frances Yee
Serial Analysis of Gene Expression of Brain Tissue From Individuals with Schizophrenia and Bipolar Disorder Yeping Sun
Epidemiologic Correlates of Interleukin-2 Receptor in Postmortem CSF and Sera of Individuals with Schizophrenia and Bipolar Disorder Linda D. Bobo
Spinophilin: Alterations In A Postsynaptic Marker in Schizophrenia Indra Dé
Screening for Viral Nucleic Acid Sequences in CSF and Brain Tissue Obtained Post Mortem from Patients with Schizophrenia and Bipolar Disorder Håkan Karlsson
PCR Methods for Differential Display of Retroviral LTR Sequences Using tRNA Binding Sites and DNA Binding Motifs of Transcription Factors as Primers Raphael P. Viscidi

Session II: Pathophysiological Mechanisms of Viral Infection and Neuropshychiatric Diseases

Protein Kinase C Signaling Cascade and Bipolar Disorder: Therapeutic Implications Husseini K. Manji
Herpes Simplex Virus Latent Infection of the Central Nervous System Richard B. Tenser
Identification of a Herpes Simplex Virus Genetic Element Involved Neurovirulence Jeng-Yang Ling
Systemic Infection Alters Neurotrophic Factor mRNA John H. Gilmore
Apoptosis in the CNS of TMEV-Infected SLJ Mice Emilia L. Oleszak
Cathecholaminergic Transmission During Newcastle Disease Virus Infection in Chicks Valluru Lokantha

Session III: Methods for the Measurement of Nucleic Acids and Proteins

Modulation of CNS Gene Expression by Mood Stabilizing Agents Husseini K. Manji
Gene Expression Discovery System (GEDSSM): A Fluorescent Differential Display Methodology for Rapid Expression Survey and Analysis of Nearly All Genes Babak Azad
Genomic Differential Display: An Alternative to Positional Cloning Cassandra Smith
Analysis of Brain Proteins by 2-Dimensional Electrophoresis N. Leigh Anderson

Session IV:  Posters

Identification of Differentially Expressed Messages From The Postmortem Brains of Schizophrenic and Bipolar Individuals Nancy L. Johnston
Correlation of Epidemiologic and Pathologic Variables with IL-2 Cytokine, IL-2 Receptor and Quinolinic Acid Levels of Individuals with Schizophrenia, Bipolar Disorder, Unipolar Depression or Normal Controls Jose D. Palton-Ortiz
Soluble Interleukin-2 Receptor Levels in Families of Patients With Schizophrenia Fiona Gaughran
Inducible-Nitric Oxide Synthase (iNOS) and Nitrotyrosine are Found in Acute But Not in Chronic Multiple Sclerosis Lesions Emilia L. Oleszak
Postnatal Herpes Simplex Virus TYpe 1 Encephalitis Affects Adults Sensorimotor Gating Function in Rats Jorgen A. Engel
CMV Infection Lorraine Brando
Calcium-Channel Dysfunction in Hippocampal Neurons Induced by Mumps Virus Infection Krister Kristensson
Hytothalamus-Hypophysis Pathology in Young Suicide Victims Z. Srebo
Schizotypy and Leadership: A Contrasting Model for the Deficit Symptoms: A Role for Sex Hormonal Dysgenesis? A.G. Alias
Schizophrenia, Affective Disorders and Infantile Autism: Ultrastructural Alterations in Platelets Sequndo Mesa
Stiff-Man Syndrome: Results of Interview and Psychologic Testing John L. Black

Session V: Plenary Speaker

What Epidemiology Can Tell About Multiple Sclerosis John F. Kurtzke

Session VI: Epidemiology and Pathogenesis of Human Neuropsychiatric Diseases

Prenatal Infection and Affective Disorders: A Tale of Two Viruses Alan S. Brown
 Seasonal Influences on First Admission of Schizophrenia and Affective Disorder In An Irish National Sample Mary Clarke
Characterization of Retroviral Sequences Isolated from Monozygotic Twins Discordant for Schizophrenia Using Representational Difference Analysis (RDA) Shiva M. Singh
Epidemic Stealth Virus Infection W. John Martin
Possible Antibody Cross-Reactivity Between Retroviral and Brain Antigens Darrenn J. Hart
Epilepsy and Schizophrenia: Alternative Responses to Brain Injury, Infection on Maldevelopment: Are Ever Larger Sample Sizes and Metanalyses Muddying the Water? Janice R. Stevens

Session VII: Autoimmunity and Psychiatric Diseases

Correlation of IL-2 Receptor Levels in CSF of Individuals With Schizophrenia, Bipolar Disorder, Unipolar Depression or Normal Controls With Immunohistochemical Localization in th Brain Maree Webster
Identical T-Cell Receptor Transcripts Are Clonally Expanded in CNS of THEV-Infected Mice With Early Acute & Late Chronic Demyelinating Disease Emelia L. Oleszak

Session VIII: Epidemiology and Pathophysiology of Borna Virus Infection

Borna Disease Virus Infection: Pathogenesis, Disease and Diagnosis in Experimentally and Naturally Infected Species Lothar Stitz
Detection and Sequence Analysis of Borna Disease Virus P24 RNA From Peripheral Blood Mononuclear Cells of Patietns With Major Depression and Schizophrenia Yashuhide Iwata
Borna Disease Virus Genomes in Autopsy Brain Samples From Control and Schizophrenia in Japan Kazuhiko Ikeda
Nuclear Targeting Activity Associated With The Amino-Terminus of Borna Diseae Virus Nucleoprotein Masahiko Kishi
Nuclear Localization of the Protein From the ORFx1 of the Borna Disease Virus Tahir H. Malik
Evolution of the Immune Response in the Central Nervous System Following Infection with Borna Disease Virus Carolyn G. Hatalski
Humoral Immunity in the Central Nervous System of Rats Infected with Borna Disease Virus Mady Hornig
T Cell Response to Borna Virus in Psychiatric Patient Koji Fukuda
The Quagmire of BDV Diagnostic Tests Kathryn M. Carbone

Session IX: Plenary Speaker and Closing

Childhood C.N.S. Infections and Adult Onset Psychosis Peter Jones
What We Know About the Epidemiology of Schizophrenia and Bipolar Disorder E. Fuller Torrey
Summary and Conclusions Robert H. Yolken